Illustration of a seated woman's lower legs where one ankle and foot are visibly fuller than the other, with a soft sock mark.

Lymphoedema

Primary and secondary lymphoedema

What is lymphoedema?

The lymphatic system is your body's drainage network — it collects the fluid that naturally leaks out of blood vessels and returns it to circulation. In lymphoedema, that drainage fails, and protein-rich fluid accumulates in the tissues, most often in a leg or arm.

It can be primary (a drainage system that was underbuilt from the start, sometimes surfacing at puberty or pregnancy) or secondary — following surgery, radiotherapy, infection, injury, or long-standing venous disease.

What does it look and feel like?

One practical sign clinicians use: if the skin fold at the base of the second toe is too thick to pinch, that points towards lymphoedema (Stemmer's sign).

Why early recognition matters

Untreated, the fluid triggers inflammation, the tissue scars and hardens, and the limb becomes vulnerable to a skin infection called cellulitis — which in turn damages the lymphatics further. Caught early, that spiral is largely preventable. This is why swelling that keeps returning deserves a name, not a shrug.

How is it diagnosed?

Mostly clinically — the history and the limb tell the story. Where it's uncertain, imaging of the lymphatics (lymphoscintigraphy or ICG lymphography) can confirm it, and an ultrasound of the veins is often done alongside, because venous disease can cause or worsen swelling and the two frequently overlap.

How is it treated?

The cornerstone is complete decongestive therapy: compression (bandaging, then fitted garments), specialised massage that redirects fluid (manual lymphatic drainage), exercise under compression, and meticulous skin care to prevent infection. It works — but it works best when started early.

Questions to bring to your doctor

Guides

Sources

  1. International Society of Lymphology — The diagnosis and treatment of peripheral lymphedema: 2020 Consensus Document (Lymphology)
  2. Grada & Phillips — Lymphedema: Pathophysiology and clinical manifestations (J Am Acad Dermatol, 2017)

KINUUM does not provide a medical diagnosis. It is a symptom-awareness guide designed to help women identify patterns worth discussing with their doctor. Always seek professional medical advice.